[PDF][PDF] Proinflammatory cytokines in HIV disease-a review and rationale for new therapeutic approaches
NC Connolly, SA Riddler, CR Rinaldo - AIDS Rev, 2005 - researchgate.net
Antiretroviral drugs currently in use for treating HIV-1 infection are very effective at
maintaining low viral loads and clinical stability, but have been limited by their inability to
eradicate virus in infected individuals, resulting in the need for indefinite therapy. The
inability of antiretroviral drug therapy to eliminate HIV-1 infection is thought to be due to
incomplete restoration of host immunity to the virus. New strategies to improve control of HIV-
1 infection during antiretroviral therapy should target enhancement of host immunity …
maintaining low viral loads and clinical stability, but have been limited by their inability to
eradicate virus in infected individuals, resulting in the need for indefinite therapy. The
inability of antiretroviral drug therapy to eliminate HIV-1 infection is thought to be due to
incomplete restoration of host immunity to the virus. New strategies to improve control of HIV-
1 infection during antiretroviral therapy should target enhancement of host immunity …